You should only follow the instructions given by the doctor who recommended the test. You do not need to undergo any special preparation before a BUN test. The test may also be done if you have a feeling to urinate frequently, fatigue, itching, trouble sleeping, muscle cramps, or swelling in legs and ankles. So, you will have to look if you have a hereditary kidney issue, high blood pressure, heart disease, or diabetes. Generally, kidney diseases will not show any early indicators. Why do I need a BUN test?Ī BUN test will be recommended as part of a routine checkup or if the healthcare provider suspects kidney disease. This test is part of a series of tests known as comprehensive metabolic panel. What is the BUN test used for?Ī BUN test can help diagnose a disorder related to Kidney. The other names for the BUN test are the Urea Nitrogen test and Serum BUN. In contrast, the BUN level tends to be lower in patients suffering from liver diseases. The level of urea and nitrogen will be higher in cases of kidney problems, heart diseases, and dehydration. If you need to know the exact amount of urea currently present in your blood, you should undergo a Blood Urea Nitrogen test, which is called BUN, in short. However, if your kidneys fail to function properly, the level of nitrogen and urea in your blood will rise. However, for the most part, your healthy kidneys discard it by flushing it out of your body through urine. Your kidneys, when they are healthy, remove the BUN, generally leaving a small amount of it in your blood. Your liver releases this BUN into your blood, and it ends up eventually in your kidneys. The liver breaks down the proteins in your food - and while doing so, the liver creates blood urea nitrogen, also called BUN. What is BUN Test?Īs already mentioned, BUN test is a diagnostic procedure to check the health of your kidneys. It essentially measures the urea nitrogen count in the blood to find out ailments related to it. Where 60 represents MW of urea and 14*2 MW of urea nitrogen.The BUN test or Blood Urea Nitrogen Test is a common blood test performed to check the proper functioning of the kidneys. Elsewhere, the concentration of urea is reported in SI units as mmol/L.ī U N m g / d L United States, Mexico, Italy, Austria, and Germany). OTC deficiency is also accompanied by hyperammonemia and high orotic acid levels.īUN is usually reported in mg/dL in some countries (e.g. Reference ranges for blood tests, comparing urea (yellow at right) to other blood constituentsĪnother rare cause of a decreased BUN is ornithine transcarbamylase deficiency, which is a genetic disorder inherited in an X-linked recessive pattern. The main causes of a decrease in BUN are malnutrition (low-protein diet), severe liver disease, anabolic state, and syndrome of inappropriate antidiuretic hormone. Hypothyroidism can cause both decreased GFR and hypovolemia, but BUN-to-creatinine ratio has been found to be lowered in hypothyroidism and raised in hyperthyroidism. The main causes of an increase in BUN are: high-protein diet, decrease in glomerular filtration rate (GFR) (suggestive of kidney failure), decrease in blood volume ( hypovolemia), congestive heart failure, gastrointestinal hemorrhage, fever, rapid cell destruction from infections, athletic activity, excessive muscle breakdown, and increased catabolism. The normal range is 2.1–7.1 mmol/ L or 6–20 mg/ dL. Interpretation īUN is an indication of renal (kidney) health. It is not considered as reliable as creatinine or BUN/creatinine ratio blood studies. The test is used to detect renal problems. Individual laboratories will have different reference ranges, as the assay used can vary between laboratories. Normal human adult blood should contain 6 to 20 mg/dL (2.1 to 7.1 mmol/L) of urea nitrogen. The liver produces urea in the urea cycle as a waste product of the digestion of protein. 6299-2, 59570-2, 12961-9, 12963-5, 12962-7īlood urea nitrogen ( BUN) is a medical test that measures the amount of urea nitrogen found in blood.
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